# Zepbound

21 Hacker News commenters recommended Zepbound and 4 criticized it, November 2025 to November 2026. It was recommended in 8 of 13 months; owners who said how long report a median of 1 years (5 owners). It meets the Hacker Approved badge rule.

**Verdict:** People recommend it for reduced hunger and substantial weight loss, and say it helped them build new habits. The most common caveat is high cost, and some report side effects.

## Why people recommend it

- Reduces hunger and cravings (3 comments): "being on a GLP1-a and able to eat what everyone else is eating but just stop and not feel hunger pains or cravings" ([source](https://news.ycombinator.com/item?id=46052224)) "zepbound to help me bury the hunger monster long enough to learn new habits" ([source](https://news.ycombinator.com/item?id=45865633)) "I would not have done it by "white knuckling". I needed some medication to help me along." ([source](https://news.ycombinator.com/item?id=45865671))
- Major weight loss reported (4 comments): "I’ve lost 110 pounds on Zepbound and still absolutely love food." ([source](https://news.ycombinator.com/item?id=46598467)) "I'm losing 5lbs a week, which is almost too much." ([source](https://news.ycombinator.com/item?id=46503810)) "since I've started Zepbound, I've lost 110 pounds" ([source](https://news.ycombinator.com/item?id=46946344))
- Positive effects beyond weight loss (2 comments): "Drugs like Zepbound have shown that over half are cured from sleep apnea after roughly a year of use" ([source](https://news.ycombinator.com/item?id=48242844)) "I'm grateful for that happy accident of a positive side effect" ([source](https://news.ycombinator.com/item?id=46049739))
- Described as life-changing (2 comments): "Zepbound + strength training is a life transforming miracle" ([source](https://news.ycombinator.com/item?id=48446355)) "Absolutely life changing." ([source](https://news.ycombinator.com/item?id=46965282))

## What people warn about

- Unpleasant side effects (3 comments): "I also had substantial mental health and physical side effects (like crying hysterically at 3am in the bathroom while vomiting) from that drug" ([source](https://news.ycombinator.com/item?id=46598699)) "seemed to get only the negative side effects and not much benefit" ([source](https://news.ycombinator.com/item?id=48707253)) "I got pancreatitis from Zepbound, but it was indirect." ([source](https://news.ycombinator.com/item?id=48702545))
- Limited benefit for some (2 comments): "seemed to get only the negative side effects and not much benefit" ([source](https://news.ycombinator.com/item?id=48707253)) "it barely works at that point" ([source](https://news.ycombinator.com/item?id=46965611))

## Alternatives hackers recommend

- [Ozempic](https://hackerapproved.com/p/ozempic.md): 52 recommend
- [Semaglutide](https://hackerapproved.com/p/semaglutide.md): 45 recommend
- [Tirzepatide (Zepbound)](https://hackerapproved.com/p/tirzepatide.md): 36 recommend
- [Retatrutide](https://hackerapproved.com/p/retatrutide.md): 23 recommend
- [Wegovy](https://hackerapproved.com/p/wegovy.md): 23 recommend

## Cite as

Hacker Approved, "Zepbound", https://hackerapproved.com/p/zepbound/ (counts from 1,795,640 Hacker News comments, November 2025 to November 2026).