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Metformin

Hacker Approved

Oral diabetes drug in Health & fitness

Cheap, out-of-patent diabetes drug that people find works well and is very safe, though side effects like diarrhea are the common caveat.

Cheap, out-of-patent diabetes drug that people find works well and is very safe, though side effects like diarrhea are the common caveat.

16 people gave an opinion

recommend it
11
criticize it
5
approval share
69%
Each figure is one person. RecommendsCriticizes

Recommended in 7 of 13 months

  1. November 2025: recommended
  2. December 2025: recommended
  3. January 2026: recommended
  4. February 2026: recommended
  5. March 2026: not recommended
  6. April 2026: not recommended
  7. May 2026: not recommended
  8. June 2026: not recommended
  9. July 2026: recommended
  10. August 2026: recommended
  11. September 2026: not recommended
  12. October 2026: recommended
  13. November 2026: not recommended (month in progress)

Why it carries the badge

  • 11 people recommend itNeeds 10 or more, met.
  • 2.2 recommenders for every criticNeeds 2 to 1 or better, met.
  • Recommended in 7 of 13 monthsNeeds 4 or more, met.

The same three rules apply to every product, and the badge can’t be bought. How the badge works

What people say about it

The reasons people give, with the number of comments that give each one. Open a reason to read what they said.

Why people recommend it

Each mark is one comment

  • Works well for many people

    “I was surprised to find that I got faster after I started taking metformin”

    Comment from 5 Nov 2025 in “Metformin (drug for blood sugar) might make you smarter”

    “fortunately metformin actually seems to be doing the job”

    Comment from 8 Feb 2026 in “FDA intends to take action against non-FDA-approved GLP-1 drugs”

    “its OTC, xtremelly safe and and it works”

    Comment from 17 Aug 2026 in “Semaglutide linked to 26% lower 5-year predicted dementia risk”
  • Very safe with few side effects

    “Metformin being very safe with the exception of a few edge cases, while providing exceptional benefit”

    Comment from 24 Dec 2025 in “Older Americans quit weight loss drugs in droves”

    “Metformin's side effects are pretty minor, I find.”

    Comment from 26 Nov 2025 in “From blood sugar to brain relief: GLP-1 therapy slashes migraine frequency”

    “its OTC, xtremelly safe and and it works”

    Comment from 17 Aug 2026 in “Semaglutide linked to 26% lower 5-year predicted dementia risk”
  • Cheap and out of patent

    “metformin is out of patent and super cheap, and I read that at least some people have had good success using it for weight loss”

    Comment from 15 Oct 2026 in “Delta’s Biscoff cookies were supposed to be temporary”

    “Cheap, effective, legal. You get to pick 2 (in the US).”

    Comment from 1 Feb 2026 in “Metformin shown to prevent Long Covid across risk groups in randomized trials”

What people warn about

Each mark is one comment

  • Side effects, including diarrhea

    “the drawback of possible side effects outweighs the potential benefit”

    Comment from 26 Nov 2025 in “From blood sugar to brain relief: GLP-1 therapy slashes migraine frequency”

    “If you ever miss having diarrhea then it is good for that.”

    Comment from 26 Apr 2026 in “A Common Diabetes Drug May Hold the Key to Stopping HIV from Coming Back”

    “It has negative side effects in many people”

    Comment from 17 Aug 2026 in “Semaglutide linked to 26% lower 5-year predicted dementia risk”

What people said

18 of the 21 comments that mention it, newest first. Each links to the original comment.

“I find the 1g tablets awkward to split with my pill splitter due to the size”

CriticizesComment from 17 Oct 2026 in “Bookofjoe's Favorite Thing: Best Pill Splitter”

“metformin is out of patent and super cheap, and I read that at least some people have had good success using it for weight loss”

RecommendsComment from 15 Oct 2026 in “Delta’s Biscoff cookies were supposed to be temporary”

“It has negative side effects in many people”

CriticizesComment from 17 Aug 2026 in “Semaglutide linked to 26% lower 5-year predicted dementia risk”

“its OTC, xtremelly safe and and it works”

RecommendsComment from 17 Aug 2026 in “Semaglutide linked to 26% lower 5-year predicted dementia risk”

“A year later all traces of gum inflammation have disappeared.”

RecommendsComment from 26 Jul 2026 in “Scientists link oral bacteria to heart disease and cognitive decline”

“It's on the World Health Organization list of essential medicines.”

RecommendsComment from 26 Jul 2026 in “Paternal metformin use associated with major birth defects (2022)”

“These have much more measurable effects than metformin, with none of the potential downsides.”

CriticizesComment from 26 Jul 2026 in “Paternal metformin use associated with major birth defects (2022)”

“If you ever miss having diarrhea then it is good for that.”

CriticizesComment from 26 Apr 2026 in “A Common Diabetes Drug May Hold the Key to Stopping HIV from Coming Back”

“and it worked shockingly well”

RecommendsComment from 8 Feb 2026 in “FDA intends to take action against non-FDA-approved GLP-1 drugs”

“fortunately metformin actually seems to be doing the job”

RecommendsComment from 8 Feb 2026 in “FDA intends to take action against non-FDA-approved GLP-1 drugs”

“Cheap, effective, legal. You get to pick 2 (in the US).”

MixedComment from 1 Feb 2026 in “Metformin shown to prevent Long Covid across risk groups in randomized trials”

“there was a concern with metformin being contaminated with carcinogenic nitrosamines”

MixedComment from 31 Jan 2026 in “Metformin shown to prevent long Covid in multiple randomized trials (2026)”

“Metformin being very safe with the exception of a few edge cases, while providing exceptional benefit”

RecommendsComment from 24 Dec 2025 in “Older Americans quit weight loss drugs in droves”

“the medications can be a godsend”

RecommendsComment from 26 Nov 2025 in “From blood sugar to brain relief: GLP-1 therapy slashes migraine frequency”

“Metformin's side effects are pretty minor, I find.”

RecommendsComment from 26 Nov 2025 in “From blood sugar to brain relief: GLP-1 therapy slashes migraine frequency”

“the drawback of possible side effects outweighs the potential benefit”

MixedComment from 26 Nov 2025 in “From blood sugar to brain relief: GLP-1 therapy slashes migraine frequency”

“Now that we have your LDL under management isn't it easier to just add metformin and gabapentin into the mix?”

CriticizesComment from 9 Nov 2025 in “Ticker: Don't die of heart disease”

“I was surprised to find that I got faster after I started taking metformin”

RecommendsComment from 5 Nov 2025 in “Metformin (drug for blood sugar) might make you smarter”

Counts come from 1,795,640 Hacker News comments, November 2025 to November 2026. How we count. Report a mistake.