# Fluoxetine

6 Hacker News commenters recommended Fluoxetine and 0 criticized it, November 2025 to November 2026. It was recommended in 5 of 13 months.

**Verdict:** People say it is safe and effective, has been life changing for some, and fixed sleep problems for one user.

## Why people recommend it

- Safe and effective, WHO endorsed (2 comments): "it has proven to be safe and effective enough that WHO believes it should be readily available in every healthcare system" ([source](https://news.ycombinator.com/item?id=46011844)) "I work in mental health, I assure you fluoxetine works very well" ([source](https://news.ycombinator.com/item?id=46041211))
- Life changing, sometimes curative results (2 comments): "fluoxetine was life changing (and potentially life saving) for her" ([source](https://news.ycombinator.com/item?id=46000215)) "Fluoxetine cured him completely and he was incredibly grateful" ([source](https://news.ycombinator.com/item?id=49489457))

## Alternatives hackers recommend

- [Ketamine](https://hackerapproved.com/p/ketamine.md): 12 recommend
- [Prozac](https://hackerapproved.com/p/prozac.md): 12 recommend
- [Bupropion](https://hackerapproved.com/p/bupropion.md): 12 recommend
- [Lexapro](https://hackerapproved.com/p/lexapro.md): 8 recommend
- [Wellbutrin](https://hackerapproved.com/p/wellbutrin.md): 6 recommend

## Cite as

Hacker Approved, "Fluoxetine", https://hackerapproved.com/p/fluoxetine/ (counts from 1,795,640 Hacker News comments, November 2025 to November 2026).